On March 16, 2021, The IBAB Research Seminar series was honoured to host Prof. Arun Shukla of IIT-Kanpur, a Wellcome Trust-DBT India Alliance Senior Fellow & EMBO Young Investigator. Talking about “‘Structure, function and modulation of G Protein-Coupled Receptors”, Prof. Shukla presented his lab’s seminal work on understanding the interaction between beta-arrestin and G Protein-Coupled Receptors, and the identification of select receptors that appear to function in a G protein-independent manner. Prof. Shukla’s lab uses state-of-the-art cryo-EM, biochemical, and cell biological assays to dissect the function of this protein family, which contains the largest number of proteins that are targeted by approved drugs. The talk was followed by an engaging discussion with Prof. Shukla.