Dr. Shruthi S Vembar

Dr. Shruthi S Vembar

Assistant Professor, Molecular Parasitology

Research Focus Key Words

Malaria, Plasmodium, Molecular parasitology, Gene regulation, RNA biology, DNA epigenetic modifications, CRISPR/Cas technologies, Host-parasite interactions, Genomics, Transcriptomics, Epigenomics


Having obtained an Integrated M.Sc. (Hons.) degree in Biological Sciences from BITS-Pilani, India, Dr. Shruthi S. Vembar moved to the University of Pittsburgh, Pittsburgh, USA, for her PhD work. For her thesis, she studied the molecular basis of Hsp70-Hsp40 interactions in budding yeast under the guidance of Dr. Jeffrey L. Brodsky. She then moved to Institut Pasteur, Paris, France, to work with Dr. Artur Scherf for her post-doctoral studies, which was supported by prestigious fellowships such as the EMBO Long-Term Fellowship and the ERC’s Marie Curie-Sklodowska International Incoming Fellowship (FP7). Thus began Dr. Vembar’s rendezvous with the malaria parasite Plasmodium falciparum, where she focused on using genome-wide approaches to understand gene regulation at the epigenetic and post-transcriptional levels, and how this affects host-parasite interaction. In 2018, Dr. Vembar returned to India to join IBAB as an Assistant Professor to head a research program in malaria molecular parasitology. She also received the prestigious Ramalingaswami Life Sciences Fellowship from the Department of Biotechnology, India, for the year 2018.


  1. UG/PG: Integrated M.Sc. (Hons.), BITS-Pilani, Pilani, India
  2. Ph.D: University of Pittsburgh, Pittsburgh, USA

Professional Experience

  1. Post-doctoral Research: Institut Pasteur, Paris, France
  2. At IBAB since December 2018

Research Interests

Dr. Vembar’s team focuses on using omics approaches to understand the molecular basis of interaction between the human host, mosquito vector and the malaria parasite, Plasmodium falciparum. Specifically, her team studies the following:

1. The role of novel epigenetic DNA base modifications in regulating gene expression during Plasmodium asexual and sexual development.

2. Functional analysis of atypical RNA-binding proteins in regulating the expression of genes involved in host-parasite interaction, including an in-depth analysis of their biochemical properties. 

3. Exploration of new modes of genome and gene regulation in Plasmodium spp. such as inteins and miniproteins.

4. Population genomics, epigenomics and transcriptomics of malaria parasites and mosquito vectors that are endemic to India.

5. The adaptation of state-of-the-art CRISPR/Cas genomic and transcriptomic engineering technologies to perform forward genetic screens in Plasmodium spp. and identify new targets for anti-malarial drug development.


  1. 2022-2025: Co-PI, SERB-Core Research Grant, Department of Science and Technology, India
  2. 2022-2025: PI, DBT-GET Grant, Department of Biotechnology, India
  3. 2021-2024: PI, SERB-Core Research Grant, Department of Science and Technology, India
  4. 2019-2024: Ramalingaswami Life Sciences Fellowship Contingency Grant, Department of Biotechnology, India
  5. 2019-2020: Industrial Research Grant, RL Fine Chem Pvt. Ltd., Bengaluru, India

Group Members
PhD Fellows

Dimple Acharya, PhD student (DBT-SRF; Registered with MAHE, Manipal; 2019-)
I have a Master’s degree in biochemistry from Sardar Patel University in Anand, Gujarat. I joined the lab in August 2019 for my PhD. I am investigating the epigenetic role of the 8-oxoGuanosine DNA modification and its reader protein OGG1 during the intra-erythrocytic stages of Plasmodium falciparum. I am also working on the DNA/RNA binding PfAlba3 to better understand its post-transcriptional gene regulatory role. Outside of the lab, I enjoy cooking, listening to music, and travelling.

Seshan D, PhD student (UGC-SRF; Registered with MAHE, Manipal; 2021-)
I have joined the molecular parasitology lab in January 2021, with an undergraduate degree from Loyola College, Chennai (2013-2016), and a postgraduate degree from Loyola College (2016-2018). At IBAB, I’ve been working on: 1. Evaluation of genome wide distribution and biological role of 6mA DNA modification and it’s regulators in Plasmodium falciparum blood stages. And, 2. Adaptation of CRISPR/Cas12 system to P. falciparum to transcriptionally repress the expression of essential genes in a conditional manner in blood stages. I love my work, and other than my work I like so many things! First thing is I like football – I started playing football from my 6th standard and still play regularly. I like playing video games, taking pictures and keeping my room clean.

Riya Mahapatra, PhD student (DST-INSPIRE JRF; 2021-)
After completing my Master’s in Human Genetics from Andhra University, I joined the molecular parasitology lab at IBAB in December 2021 as a Ph.D. student. My interest lies in understanding the role of RNA-binding proteins in post-transcriptionally regulating gene expression in Plasmodium falciparum. Apart from that, I hold a significant interest in Immunology and cancer immunotherapeutics. Besides my academic interests, in my leisure time, I like to volunteer for workshops, work in NGOs, paint, write blogs, and travel to new places.

Anitha Bavikatte, PhD student (IBAB JRF; 2022-)
I completed my Master’s of Technology in Bioinformatics from PES Institute of Technology, Bengaluru. After my Master’s, I worked as a Bioinformatics Analyst in a genomics company, Leucine Rich Bio Pvt Ltd, for 3 years, where I had the opportunity to work on RNA-seq, variant calling and microarray analysis pipelines. After that, I joined as a Project Assistant in the Bio-IT centre of IBAB in 2020 and collaborated on a variety of projects in the domain of population genomics and RNA-seq analysis. I also helped conduct several workshops involving Linux programming and NGS analysis. Since 2022, I am a PhD research scholar in the molecular parasitology lab at IBAB. My thesis addresses the dissection of the population structure and diversity of Indian malaria parasites and indigenous vectors of infectious diseases using an omics approach. Apart from research, I like painting and reading books.

Varsha HJ, PhD student (DST-INSPIRE JRF; 2022-)
I completed my Integrated MSc in Biological Sciences from Bangalore University. As a researcher, I was always interested in understanding the genetic basis of diseases, host-pathogen interactions, and the biology behind them. I joined the Molecular parasitology Lab in 2022 as a Ph.D. student and am involved in understanding the role of R-loops in the malarial parasite, Plasmodium falciparum. Apart from academic research, I like spending my free time painting, drawing, and doing butterfly photography.
Vaishakh V M, PhD student (UGC JRF; 2024-)
“I’ve joined the molecular parasitology lab in IBAB after completing my Masters in Zoology from Central University of Kerala (2022). I am interested in research focusing on disease biology and regenerative medicine. Here my work will focus on understanding the functioning of Alba family proteins in Plasmodium falciparum and other RNA-binding proteins functioning in gametocyte differentiation of the same. Outside the lab I enjoy playing cricket, watching movies, exploring places and like to stay updated with current affairs, science and tech.”

Project Fellows

Aabhas Martand, DBT-Project JRF (2022-)
I joined the lab in early 2022 and my work is centered around adapting CRISPR-Cas13 systems to be used in Plasmodium transcriptome engineering. I am interested in molecular biology and cellular biology while the implementations of machine learning and artificial intelligence in biology fascinate me decidedly. When I am not experimenting in the lab, it is probable I might be found experimenting in the kitchen. Apart from a love for good food, I have a love for road trips, gadgets, and photography.
Sowmiya Ramesh, DBT-Project JRF (2022-)
As a microbiologist, I was always fascinated by how microorganisms evade host immune mechanisms to cause infections. After completing my Master’s in Microbiology from Pondicherry University, I joined IBAB as a JRF in April My work involves establishment of CRISPR-Cas13 as a transcriptome engineering tool in malarial parasites. Apart from that, I also do miniature art, painting, calligraphy, cycling and swimming.
Ekta Dharamraj, DST-Project SRF (2023-)
“I joined Prof. Vembar’s lab in September 2023 as an SRF. I have recently defended my Ph.D. thesis in Plant molecular genetics and transgenesis from IIT Kharagpur. After my Ph.D. I wanted to gain skills and expertise in microbial systems and learn protein engineering and cell-culture work; hence, I joined Prof. Vembar’s Molecular Parasitology lab. Broadly, my work involves the exploration of new epigenetic pathways in the malaria parasite Plasmodium falciparum as targets from drug design. I am studying the presence of 8-oxoGuanosine modifications and P. falciparum protein OGG1 for its role in the BER pathway. Apart from work, I love movies, music, painting, and mountain travel.”
Raee Dharmopadhye, Project Assistant (2024-)
“I have completed my M.E. in Biotechnology from Birla Institute of Technology and Science, Pilani in July 2023. After my Master’s, I worked for one year in a consulting firm called PharmaACE Analytics, Pvt. Ltd. and joined IBAB as a Project Assistant in January 2024. My work at the Molecular Parasitology Lab at IBAB comprises of studying and establishing CRISPR-Cas13 systems for transcriptome engineering in malaria parasite. Apart from research, I love to cook, travel and watch movies.”

Spring 2024 (ongoing)

Dhanya Hegde (MSc12, IBAB)
“CRISPR/Cas13 systems offer a promising alternative to RNA interference due to their reduced off-target effects. Cas13 endonucleases have been extensively studied. Despite the discovery of smaller Cas13 variants like Cas13d (~930 amino acids), their size remains a challenge for efficient RNA editing and therapeutic delivery. The alumni of the lab have shortlisted some compact cas13 proteins (300-699 amino acids) in the NCBI non-redundant protein database. The aim of our study is to find more such proteins, and experimentally validate their RNA targeting activity, which will revolutionize transcriptomic engineering and hold promise for therapeutic applications. During the course of this project, I aim to sharpen my skills in both computational analysis and experimental techniques, while also fostering a deeper understanding of scientific inquiry. In my leisure time, I like trekking, reading novels and photography.”
Ritwik Maity (MSc12, IBAB)
“Closely related unicellular protists show intriguing variability in host parasitism. Recent studies in our lab have revealed that among Amoebozoan and Discoban protists, the diversification of histone tails plays a crucial role in distinguishing parasites from non-parasites. My work focuses on a comprehensive analysis of the epigenetic machinery governing post-translational modifications of histone tails, especially the writer, reader, and eraser enzymes. I use various computational tools and databases to delve into these complex evolutionary relationships. My hobbies include traveling, cultural exploration and watching movies.”
Kanishka Ojha, MSc Dissertation Intern (Devi Ahilya Vishwavidyalaya, Indore, MP)
“I am a postgraduate Bioinformatics student from Devi Ahilya University (Indore, MP), currently pursuing my MSc dissertation project in the Molecular Parasitology lab. I joined the lab as an intern in January 2024. My focus revolves around unravelling the intricacies of epigenetic regulation through a comprehensive genome-wide distribution analysis of novel DNA base modifications. Employing a bioinformatics approach, I delve into the dynamic landscape of the malaria parasite genome to identify and characterize previously undiscovered DNA base modifications. This exploration aims to shed light on the role these modifications play in the epigenetic regulation of the parasite. In my free time, I enjoy stargazing, baking, reading books
and travelling.”
Gargi Tikoo, MSc Dissertation Intern (Shoolini University of Biotechnology and Management Sciences, Solan, HP)
“I am a postgraduate Biotechnology student from Shoolini university, Solan (HP), currently pursuing my M.Sc. Dissertation Project in the Molecular Parasitology Lab. I have joined the lab in January 2024 and I am working on a compelling research project focusing on the functional characterization of a putative plant N-Methyltransferase involved in nicotinate detoxificationin Trigonella foenum graecum, commonly known as fenugreek or methi. Fenugreek, renowned for its medicinal properties, produces various secondary metabolites, including trigonelline, with promising anti-diabetic, anti-obesity, and neuro-protective attributes. However, the enzyme responsible for trigonelline biosynthesis remains elusive. Through transcriptomics and metabolomics analyses, a putative nicotinate N-methyltransferase highly expressed in fenugreek leaf tissue has been identified. My aim is to undertake the functional characterization of this enzyme utilizing biochemical and in silico approaches. Apart from this my research interest lies in Cancer Biology and Computational Biology. Outside the lab, I do cycling, swimming and find joy in playing sports such as basketball, badminton and want to travel and explore new places.”
Prashanth Y A (MSc Dissertation Intern, Univ. of Mysore, KA)
“THE MORE WE KNOW, THE MORE WE REALIZE THERE IS YET TO KNOW” – is the true essence of biology. I’m a postgraduate biotechnology student from University of Mysore currently interning at the Molecular Parasitology lab. I’m very much interested in identifying new targets for developing novel drugs, especially a rookie killer for cancer cells. For my internship, I am working on biochemically characterizing the PfRNase H2 protein complex from Plasmodium falciparum. In my free time, I love to garden and make miniature constructions in my free time. I also enjoy analysing the evolving geopolitical situations across the globe, cycling and listening to music.”

Lab alumni

Project Fellows and Project Assistants

  • Jaiganesh S, Project Assistant (2.5 yrs; 2021-2023) — now enrolled in the iMM LisbonBioMed International PhD program, Lisbon, Portugal
  • Anjani Rao, Project Assistant (1.5 yrs; 2022-2023) — now pursuing a PhD at the University of Montpelier, France
  • Elvis Christie, Project JRF (1 yr; 2022-2023) — n/k
  • Anitha Bavikatte, Project Assistant (2020-2022) — now pursuing a PhD at IBAB
  • Sneha Murthy, Project Assistant (2020-2022) — now pursuing a PhD at the Dalhousie University, Halifax, Canada
  • Mohan Govindasamy, Project JRF (2021-2022) — now pursuing a PhD at National University of Ireland, Galway, Ireland
  • Kapil Pareek, Project Assistant (2021) — now pursuing a PhD at the Universitätsklinikum Erlangen, Germany
  • Cynthia Francis David (2021) — now working at DBT-InStem, Bengaluru
  • Ambika Doddamani, Project Assistant (2019-2021) — now working at Syngene, Bengaluru
  • Venkat Mudiyam, Project Assistant (2019-2021) — now pursuing a PhD at the University of Lille, France
  • Venitha Bernard, Project Assistant (2019-2020) — now pursuing a PhD at Penn State University, State College, PA, USA
  • Shilpa Ajit, Project Assistant (2019) — now working at Jubilant Biosys Limited,Bengaluru

*Though not included here, IBAB MSc Thesis Interns Chondamma BC and Monoswi Chakraborty worked briefly as Project Assistants to wrap up their thesis work before moving abroad for their PhD

External Thesis Interns
Spring 2023

  • Dikhita Basishtha, MSc Dissertation Intern (Avinashilingam University, Coimbatore) — degree ongoing
  • Sowmyaa Sridhar, BTech Dissertation Intern (PES University, Bengaluru) — degree ongoing

Spring 2022

  • Amruta Kulkarni, BTech Dissertation Intern (DY Patil Deemed to be University, Mumbai) — now working at Cisco, Bengaluru
  • Shatabdi Das, MSc Dissertation Intern (Amity University, Gwalior) — now working in MarketsandMarkets Research Company as a Research Associate in Healthcare

Spring 2021

  • Jaiganesh S, MSc Dissertation Intern (VIT, Vellore) — now working in my group as a Project Assistant 2019-2020
  • Nisha Madhukar, MSc Dissertation Intern (Banasthali University, Rajasthan) — now working as an Associate Business Analyst at Aastey, Bengaluru

IBAB MSc Interns
Spring 2023 (MSc11)

  • Divya S — now working at JNCASR, Bengaluru
  • Varshini S — now working at Eli Lilly, Bengaluru
  • Nihar Lakhe — now working at Strand Life Sciences, Bengaluru

Spring 2022 (MSc10)

  • Monsowi Chakraborty, MSc Dissertation Intern (IBAB) — now pursuing a PhD at Montana State University, Bozeman, USA
  • Muskaan Sharma, MSc Dissertation Intern (IBAB) — now working at Novartis, Hyderabad
  • Kanika Bhatia, MSc Dissertation Intern (IBAB) — now working at Eli Lilly, Bengaluru
  • Thrilok Gowda, MSc Dissertation Intern (IBAB) — now working at Thermo Fisher Scientific, Bengaluru

Spring 2021 (MSc09)

  • Chondamma Bollachettira Vijaya, MSc Dissertation Intern (IBAB) — now pursuing a PhD at Ludwig Maximilian University of Munich, Germany
  • Aishwarya Rajurkar, MSc Dissertation Intern (IBAB) — now pursuing a PhD at Baylor College of Medicine, Houston, USA
  • Ramyashree HJ, MSc Dissertation Intern (IBAB) — now working at Strand Life Sciences, Bengaluru

Spring 2020 (MSc08)

  • Maanasa Bhaskaran, MSc Dissertation Intern (IBAB) — now pursuing a PhD at the University of Lille, France
  • Vishnu Ashok, MSc Dissertation Intern (IBAB) — now working at JNCASR, Bengaluru
  • Anshu Chitkara, MSc Dissertation Intern (IBAB) — now working at Novartis, Hyderabad
  • Devangshu Nandi, MSc Dissertation Intern (IBAB) — n/k

Spring 2019 (MSc07)

  • Chaitanyaraj Jadeja, MSc Dissertation Intern (IBAB) — now working at Strand Life Sciences, Bengaluru 
  • Subrata Mishra, MSc Dissertation Intern (IBAB) — now pursuing a PhD at IIT-Mumbai, Mumbai

Short-term Interns

  • Shrujana Kandadai, Int. MSc Summer Intern (VIT, Vellore) — degree ongoing
  • Deepta Beji, Int. MSc Summer Intern (VIT, Vellore) — degree ongoing
  • Paarangi Chawla, B.Tech Summer Intern (IIT, Rourkee) — degree ongoing


  • Sowmyaa Sridhar, BTech Intern (PES University, Bengaluru) — degree ongoing


  • Preshita Dave, BTech Intern (RVCE, Bengaluru) — now working as Bioinformatics Specialist I at Massachusetts General Hospital, Boston, USA, after obtaining a Masters from Boston University, USA
  • Tanvi Garg, BTech Summer Intern (IIT-Kharagpur) — now pursuing a Masters at KTH Royal Institute of Technology, Stockholm, Sweden


  • Ria Sonigara, BTech Summer Intern (IIT-BHU) — degree ongoing


  • Zara Anwar, MSc Summer Intern (Dayanand Sagar University, Bengaluru) —  now working at Celegence, Bengaluru


  1. Berglar AV, Vembar SS, Gopaul DN. Localization of the putative recombinase Pf-int to the apicoplast of Plasmodium falciparum.
    Deposited in biorxiv. https://doi.org/10.1101/2021.10.12.464051
  2. Nadig S+, MurthyS, Vandanashree M, Hosahalli SS, Gopal B+ and VembarSS.
    Draft Genome Sequence of Staphylococcus aureus LVP-7 (ST88), a community-associated isolate from an eye infection.
    Microbiol. Resour. Announc. 2021, Feb 18;10(7):e00077-21.
    +Corresponding authors
  3. Rawat M, Kanyal A, Sahasrabudhe S, Vembar SS, Lopez-Rubio JJ, Karmodiya K.
    Histone acetyltransferase PfGCN5 regulates stress responsive and artemisinin resistance related genes in Plasmodium falciparum.
    Sci. Rep. 2021, Jan 13;11(1):852.
    An initial version deposited in biorxiv: https://doi.org/10.1101/679100
  4. Bernard V, Moudgalya S, Reegan D, Sreekanthreddy P, Mohan A, Hosahalli S, Vembar SS+, Ghosh S+.
    Whole Genome Sequences of Aedes aegypti (Linn.) Field Isolates from Southern India. 
    +Corresponding authors
  5. Hammam E, Ananda G, Sinha A, Scheidig-Benatar C, Bohec M, Preiser PR, Dedon PC, Scherf A+, Vembar SS+.
    Discovery of a new predominant cytosine DNA modification linked to gene expression in malaria parasites.
    Nucleic Acids Res. 2020.Jan 10;48(1):184-199. 
    +Corresponding authors    
  6. Berglar A+, Vembar SS.
    Past, present and future of malaria prevalance and eradication in the light of climate change. 
    Book chapter in: Elsevier Science’s Encyclopedia of Environmental Health, 2e. 2019.
    +Corresponding author
  7. Herrera-Solorio AM, Vembar SS, Macpherson CR, Lozano-Amado D, Meza GR, Xoconostle-Cazares B, Martins RM, Chen P, Vargas M, Scherf A+, Hernandez-Rivas R+.
    Clipped histone H3 is integrated into nucleosomes of DNA replication genes in the human malaria parasite Plasmodium falciparum.
    EMBO Rep. 2019 e46331.
    +Corresponding authors
  8. Shurtleff MJ, Itzhak DN, Hussmann JA, Schirle Oakdale NT, Costa EA, Jonikas M, Weibezahn J, Popova KD, Jan CH, Sinitcyn P, Vembar SS, Hernandez H, Cox J, Burlingame AL, Brodsky JL, Frost A, Borner GH+, Weissman JS+.
    The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins.
    Elife. 2018 May 29;7. pii: e37018. 
    +Corresponding authors
  9. Zanghì G, Vembar SS, Baumgarten S, Ding S, Guizetti J, Bryant JM, Mattei D, Jensen ATR, Rénia L, Goh YS, Sauerwein R, Hermsen CC, Franetich JF, Bordessoulles M, Silvie O, Soulard V, Scatton O, Chen P, Mecheri S, Mazier D+, Scherf A+.
    A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection.
    Cell Rep. 2018 Mar 13;22(11):2951-2963.
    +Corresponding authors
  10. Sierra-Miranda M, Vembar SS, Delgadillo DM, Ávila-López PA, Herrera-Solorio AM, Lozano Amado D, Vargas M, Hernandez-Rivas R.
    PfAP2Tel, harbouring a non-canonical DNA-binding AP2 domain, binds to Plasmodium falciparum telomeres.
    Cell Microbiol. 2017 Sep;19(9). Epub 2017 May 3.
  11. Cubi R*, Vembar SS*, Biton A, Franetich JF, Bordessoulles M, Sossau D, Zanghi G, Bosson-Vanga H, Benard M, Moreno A, Dereuddre-Bosquet N, Le Grand R, Scherf A, Mazier D.
    Laser capture microdissection enables transcriptomic analysis of dividing and quiescent liver stages of Plasmodium relapsing species.
    Cell Microbiol. 2017 Aug;19(8). Epub 2017 Mar 13.
    *First authors
  12. Vembar SS+, Seetin M, Lambert C, Nattestad M, Schatz MC, Baybayan P, Scherf A, Smith ML+.
    Complete telomere-to-telomere de novo assembly of the Plasmodium falciparum genome through long-read (>11 kb), single molecule, real-time sequencing.
    DNA Res. 2016 Aug;23(4):339-51. Epub 2016 Jun 26.
    +Corresponding authors
  13. Vembar SS+, Droll D, Scherf A. Translational regulation in blood stages of the malaria parasite Plasmodium spp.: systems-wide studies pave the way.
    Wiley Interdiscip Rev RNA. 2016 Nov;7(6):772-792. Epub 2016 May 26. Review.
    +Corresponding author
  14. Scherf A+, Malmquist N, Martins RM, Vembar SS, Lopez-Rubio JJ.
    Gene regulation: New insights and possible intervention strategies. 
    Book chapter in: Wiley-IUBMB Series Recent Advances in Malaria. 2016.
    +Corresponding author
  15. Vembar SS+, Macpherson CR, Sismeiro O, Coppée JY, Scherf A+.
    The PfAlba1 RNA-binding protein is an important regulator of translational timing in Plasmodium falciparum blood stages.
    Genome Biol. 2015 Sep 28;16:212.
    +Corresponding authors
  16. Vembar SS, Scherf A, Siegel TN.
    Noncoding RNAs as emerging regulators of Plasmodium falciparum virulence gene expression.
    Curr Opin Microbiol. 2014 Aug;20:153-61. Epub 2014 Jul 12. Review.
  17. Chêne A*, Vembar SS*, Rivière L, Lopez-Rubio JJ, Claes A, Siegel TN, Sakamoto H, Scheidig-Benatar C, Hernandez-Rivas R, Scherf A.
    PfAlbas constitute a new eukaryotic DNA/RNA-binding protein family in malaria parasites.
    Nucleic Acids Res. 2012 Apr;40(7):3066-77. Epub 2011 Dec 13.
    *First authors
  18. Vembar SS, Jonikas MC, Hendershot LM, Weissman JS, Brodsky JL.
    J domain co-chaperone specificity defines the role of BiP during protein translocation.
    J Biol Chem. 2010 Jul 16;285(29):22484-94. Epub 2010 Apr 29.
  19. Vembar SS, Jin Y, Brodsky JL, Hendershot LM.
    The mammalian Hsp40 ERdj3 requires its Hsp70 interaction and substrate-binding properties to complement various yeast Hsp40-dependent functions.
    J Biol Chem. 2009 Nov 20;284(47):32462-71. Epub 2009 Sep 11.
  20. Vembar SS, Brodsky JL.
    One step at a time: endoplasmic reticulum-associated degradation.
    Nat Rev Mol Cell Biol. 2008 Dec;9(12):944-57. Epub 2008 Nov 12. Review.
  21. Feng D, Zhao X, Soromani C, Toikkanen J, Römisch K, Vembar SS, Brodsky JL, Keränen S, Jäntti J.
    The transmembrane domain is sufficient for Sbh1p function, its association with the Sec61 complex, and interaction with Rtn1p.
    J Biol Chem. 2007 Oct 19;282(42):30618-28.


  1. Dr. Melissa Laird-Smith, University of Louisville, Kentucky, USA
  2. Prof. Eric Greer, Washington University, St. Louis, USA
  3. Dr. Bhaswar Ghosh, IIIT-Hyderabad, India
  4. Prof. Sandeep Sundriyal, BITS-Pilani, Pilani, India
  5. Dr. Suchi Tyagi, NIMR, New Delhi, India
  6. Dr. Ajeet Mohanty, NIMR, Goa, India
  7. Dr. Niti Kumar, CSIR-CDRI, Lucknow, India
  8. Dr. Sanjay Ghosh, IBAB, Bengaluru, India
  9. Dr. Shubhada Hegde, IBAB, Bengaluru, India
  10. Dr. Daniel Reegan, National Centre for Disease Control, Bengaluru, India
  11. Prof. Artur Scherf, CNRS, INSERM, Institut Pasteur, Paris, France
  12. Dr. Benoit Gamain, CNRS, INSERM, INTS, Paris, France
  13. Dr. Abhilash Mohan, Merck Group, Bengaluru, India
  14. Prof. B. Gopal, IISc, Bengaluru, India
  15. Prof. Vir Negi, JIPMER, Puducherry, India
  16. Dr. Christina Mary Mariaselvam, JIPMER, Puducherry, India
  17. Prof. R. Srivatsan, IBAB, Bengaluru, India
  18. Dr. Sweta Srivastava, St. Johns National Academy of Health Sciences, Bengaluru, India


Institute of Bioinformatics and Applied Biotechnology
Biotech Park, Electronic City Phase I,
Bengaluru 560100,


285 289 00/01/02, extension 122