WE ARE COMMITED TO

In their most recent publication titled “The work, goals, challenges, achievements, and recommendations of orphan medicinal product organizations in India: an interview-based study”, published on Nov 4, 2019 in Orphanet Journal of Rare Diseases, IBAB faculty Dr. Gayatri Saberwal and Post-doctoral Fellow Dr. Mohua Chakraborty address the lack of R&D in India to tackle life-debilitating rare diseases that are prevalent in the Indian population. Dr. Mohua interviewed select Indian organizations that are engaged in orphan medicinal product development, and in this publication, she highlights the ongoing efforts of these organizations. Overall, the authors encourage increased investment in rare disease R&D, particularly from a science policy perspective.

In collaboration with research groups from the National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, IBAB faculty Dr. S. Thiyagarajan recently published a paper in Scientific Reports describing the oxidation of the UQCRC1 subunit of mitochondrial Respiratory Complex III in muscular dystrophy patients. Using molecular dynamic simulations, the authors identified local structural changes in the Trp395 site of UQCRC1, which is targeted for oxidation; this could potentially explain the impaired electron flow via the ETC and consequently reduced mitochondrial function that is observed in muscular dystrophy patients.

We are super enthused to introduce the blog-style ‘IBAB Insider’ @ http://ibab.ac.in/smt-blog/index.html. A brainchild of the IBAB Social Media Team, ‘IBAB insider’ is a platform for all IBABians to express their personal and professional experiences in the form of blog posts. It is a part of the official IBAB website and all IBABians, past and present, are invited to actively contribute to it. It contains introductory blog posts written by Chondamma, Tejashwini and Rohit, members of the social media team, about their IBAB experience.