Prof. C M Gupta

Prof. C M Gupta

Distinguished Professor and Infosys Chair, Infectious Disease Biology

Research Focus Key Words

Protozoan parasites, Actin and actin binding proteins, Leishmania actin cell biology, Drug targeting, Nanoparticles as drug carriers

Background

Medicinal & Bio-organic Chemistry, Membrane Biochemistry, Drug targeting, Parasite Molecular Cell Biology

Education

Ph.D. Organic Chemistry, Agra University, Agra

Post-doctoral work

  1. Research Associate (with Prof. H.G. Khorana), M.I.T., Cambridge, MA, U.S.A., 1975-1978
  2. Post-doctoral Fellow (with Dr.John G.Moffat), Inst. Mol. Biol., Syntex Research, Palo Alto, CA, U.S.A., 1973-1975
  1. Scientist, CDRI, Lucknow, 1978- 1992
  2. Visiting Scientist, M.I.T., Cambridge, MA, U.S.A., 1981
  3. Director, IMTech, Chandigarh, 1992-1997
  4. Director-Incharge, ITRC, Lucknow, 2005-2007
  5. Director, CDRI, Lucknow, 1997-2007
  6. Distinguished Biotechnologist, CDRI, Lucknow, 2007 –2009

Research Interest Profile

Published about 130 original papers and about 20 review articles/ book chapters detailing the contributions made in the above areas

Group members

  1. Rani Bajaj : Ph.D student
  2. Purna Sudha Bindu Ambaru : Ph.D student
  3. Dr. Raja : Post Doctoral fellow

Current collaborators

  1. Dr. H. S. Subramanya
  2. Dr. S. Thiyagarajan

Research Publications

Dr. Gupta has published about 130 original papers and about 20 review articles/ book chapters. Recent publications include the following:

TitleCited byYear
B Ambaru, GM Gangadharan, HS Subramanya, CM Gupta
Profilin is involved in G1 to S phase progression and mitotic spindle orientation during Leishmania donovani cell division cycle
Plos one 17 (3), e0265692
2022
CM Gupta, B Ambaru, R Bajaj
Emerging Functions of Actins and Actin Binding Proteins in Trypanosomatids
Frontiers in Cell and Developmental Biology 8, 1109
62020
B Ambaru, A Gopalsamy, TVS Tammana, HS Subramanya, CM Gupta
Actin sequestering protein, profilin, regulates intracellular vesicle transport in Leishmania
Molecular and Biochemical Parasitology 238, 111280
42020
R Bajaj, B Ambaru, CM Gupta
Deciphering the role of UBA-like domains in intraflagellar distribution and functions of myosin XXI in Leishmania
PloS one 15 (4), e0232116
32020
K Murugesan, P Srinivasan, R Mahadeva, CM Gupta, W Haq
Tuftsin-Bearing Liposomes Co-Encapsulated with Doxorubicin and Curcumin Efficiently Inhibit EAC Tumor Growth in Mice
International Journal of Nanomedicine 15, 10547
22020
K Murugesan, J Koroth, PP Srinivasan, A Singh, S Mukundan, SS Karki, …
Effects of green synthesised silver nanoparticles (ST06-AgNPs) using curcumin derivative (ST06) on human cervical cancer cells (HeLa) in vitro and EAC tumor bearing mice models
International Journal of Nanomedicine 14, 5257
412019
CM Gupta
Phospholipids in disease
Phospholipids Handbook, 895-908
102018
AR Nayak, SS Karade, VK Srivastava, AK Rana, CM Gupta, …
Structure of Leishmania donovani coronin coiled coil domain reveals an antiparallel 4 helix bundle with inherent asymmetry
Journal of Structural Biology 195 (1), 129-138
52016
G Kumar, LP Kajuluri, CM Gupta, AA Sahasrabuddhe
A twinfilin‐like protein coordinates karyokinesis by influencing mitotic spindle elongation and DNA replication in Leishmania
Molecular Microbiology 100 (1), 173-187
52016
R Srivastava, L Prasadareddy Kajuluri, N Pathak, CM Gupta, …
Oligomerization of coronin: Implication on actin filament length in Leishmania
Cytoskeleton 72 (12), 621-632
72015
CM Gupta, S Thiyagarajan, AA Sahasrabuddhe
Unconventional actins and actin-binding proteins in human protozoan parasites
International Journal for Parasitology 45 (7), 435-447
92015
K Singh, NK Veluru, V Trivedi, CM Gupta, AA Sahasrabuddhe
An actin‐like protein is involved in regulation of mitochondrial and flagellar functions as well as in intramacrophage survival of Leishmania donovani
Molecular Microbiology 91 (3), 562-578
72014
VK Srivastava, AK Rana, AA Sahasrabuddhe, CM Gupta, JV Pratap
Cloning, overexpression, purification and crystallization of the CRN12 coiled-coil domain from Leishmania donovani
Acta Crystallographica Section F: Structural Biology and Crystallization …
42013
G Kumar, R Srivastava, K Mitra, AA Sahasrabuddhe, CM Gupta
Overexpression of S4D mutant of Leishmania donovani ADF/cofilin impairs flagellum assembly by affecting actin dynamics
Eukaryotic cell 11 (6), 752-760
122012
PP Pathak, SK Pulavarti, A Jain, AA Sahasrabuddhe, CM Gupta, A Arora
Solution structure and dynamics of ADF/cofilin from Leishmania donovani
Journal of structural biology 172 (3), 219-224
112010
SS Katta, TVS Tammana, AA Sahasrabuddhe, VK Bajpai, CM Gupta
Trafficking activity of myosin XXI is required in assembly of Leishmania flagellum
Journal of cell science 123 (12), 2035-2044
342010
P Kapoor, A Kumar, R Naik, M Ganguli, MI Siddiqi, AA Sahasrabuddhe, …
Leishmania actin binds and nicks kDNA as well as inhibits decatenation activity of type II topoisomerase
Nucleic acids research 38 (10), 3308-3317
112010
TVS Tammana, AA Sahasrabuddhe, VK Bajpai, CM Gupta
ADF/cofilin-driven actin dynamics in early events of Leishmania cell division
Journal of Cell Science 123 (11), 1894-1901
352010
R Kumar, S Gupta, R Srivastava, AA Sahasrabuddhe, CM Gupta
Expression of a PTS2-truncated hexokinase produces glucose toxicity in Leishmania donovani
Molecular and biochemical parasitology 170 (1), 41-44
152010
AA Sahasrabuddhe, RC Nayak, CM Gupta
Ancient Leishmania coronin (CRN12) is involved in microtubule remodeling during cytokinesis
Journal of cell science 122 (10), 1691-1699
232009
SS Katta, AA Sahasrabuddhe, CM Gupta
Flagellar localization of a novel isoform of myosin, myosin XXI, in Leishmania
Molecular and biochemical parasitology 164 (2), 105-110
332009
AA Sahasrabuddhe, CM Gupta
Trypanosomatid actins: a new class of eukaryotic actins.
The cytoskeleton of parasitic protozoa, 15-23
12009
TVS Tammana, AA Sahasrabuddhe, K Mitra, VK Bajpai, CM Gupta
Actin‐depolymerizing factor, ADF/cofilin, is essentially required in assembly of Leishmania flagellum
Molecular microbiology 70 (4), 837-852
522008
P Kapoor, AA Sahasrabuddhe, A Kumar, K Mitra, MI Siddiqi, CM Gupta
An unconventional form of actin in protozoan hemoflagellate, Leishmania
Journal of Biological Chemistry 283 (33), 22760-22773
312008
S Raza, AA Sahasrabuddhe, CM Gupta
Nuclear localization of an actin-related protein (ORF LmjF21. 0230) in Leishmania
92007
R Maurya, CM Gupta
Traditional herbs for modern medicine
Tech monitor 43, 23-36
112006
RC Nayak, AA Sahasrabuddhe, VK Bajpai, CM Gupta
A novel homologue of coronin colocalizes with actin in filament-like structures in Leishmania
Molecular and biochemical parasitology 143 (2), 152-164
282005
M Owais, CM Gupta
Targeted drug delivery to macrophages in parasitic infections
Current drug delivery 2 (4), 311-318
612005
CM Gupta, W Haq
Tuftsin-bearing liposomes as antibiotic carriers in treatment of macrophage infections
Methods in enzymology 391, 291-304
412005
R Maurya, S Srivastava, DK Kulshreshta, CM Gupta
Traditional remedies for fertility regulation
Current medicinal chemistry 11 (11), 1431-1450
1072004
AA Sahasrabuddhe, VK Bajpai, CM Gupta
A novel form of actin in Leishmania: molecular characterisation, subcellular localisation and association with subpellicular microtubules
Molecular and biochemical parasitology 134 (1), 105-114
812004
A Tripathi, CM Gupta
Transbilayer translocation of membrane phosphatidylserine and its role in macrophage invasion in Leishmania promastigotes
Molecular and biochemical parasitology 128 (1), 1-9
402003
M Owais, S Bhattacharya-Misra, W Haq, CM Gupta
Immunomodulator tuftsin augments antifilarial activity of diethylcarbamazine against experimental brugian filariasis
292003
GS Rao, AK Bachhawat, C Gupta
Two-hybrid-based analysis of protein–protein interactions of the yeast multidrug resistance protein, Pdr5p
Functional & integrative genomics 1 (6), 357-366
162002
SS Jana, DJ Bharali, P Mani, A Maitra, CM Gupta, DP Sarkar
Targeted cytosolic delivery of hydrogel nanoparticles into HepG2 cells through engineered Sendai viral envelopes
FEBS letters 515 (1-3), 184-188
382002
S Krishnamurthy, BL Dixit, CM Gupta, S Milewski, R Prasad
ABC transporters Cdr1p, Cdr2p and Cdr3p of a human pathogen Candida albicans are general phospholipid translocators
Yeast 19 (4), 303-318
1172002
AK Agrawal, A Agrawal, A Pal, PY Guru, CM Gupta
Superior chemotherapeutic efficacy of amphotericin B in tuftsin-bearing liposomes against Leishmania donovani infection in hamsters
Journal of drug targeting 10 (1), 41-45
682002
M Owais, AK Masood, JN Agrewala, D Bisht, CM Gupta
Use of liposomes as an immunopotentiating delivery system: in perspective of vaccine development
Scandinavian journal of immunology 54 (1‐2), 125-132
322001
AK Agrawal, A Puri, W Haq, CM Gupta
Enhanced Immunostimulant Activity and Protective Effect of a Synthetic Lipopeptide after Liposomization Against Plasmodium berghei Infection in Mice
Journal of drug targeting 9 (4), 231-239
42001
M Owais, CM Gupta
Liposome‐mediated cytosolic delivery of macromolecules and its possible use in vaccine development
European Journal of Biochemistry 267 (13), 3946-3956
672000
AK Agrawal, CM Gupta
Tuftsin-bearing liposomes in treatment of macrophage-based infections
Advanced drug delivery reviews 41 (2), 135-146
1592000
AK Agrawal, CM Gupta
Antibody-bearing liposomes as chloroquine vehicles in treatment of murine malaria
Drug Targeting, 227-239
52000
M Owais, CM Gupta
Liposome mediated induction of CD8+ T lymphoctyes by immunization with v3 loop region of HIV gp120.
FASEB JOURNAL 13 (4), A634-A634
1999
V Puri, A Arora, CM Gupta
Probing the role of C‐1 ester group in Naja naja phospholipase A2–phospholipid interactions using butanetriol‐containing phosphatidylcholine analogues
European journal of biochemistry 259 (3), 586-591
11999
S Dogra, S Krishnamurthy, V Gupta, BL Dixit, CM Gupta, D Sanglard, …
Asymmetric distribution of phosphatidylethanolamine in C. albicans : possible mediation by CDR1, a multidrug transporter belonging to ATP binding cassette (ABC …
Yeast 15 (2), 111-121
851999
V Puri, CM Gupta
Out-to-in translocation of butanetriol-containing phospholipid analogs in human erythrocyte membrane
Biochimica et Biophysica Acta (BBA)-Biomembranes 1373 (1), 59-66
51998
BL Dixit, CM Gupta
Role of the actin cytoskeleton in regulating the outer phosphatidylethanolamine levels in yeast plasma membrane
European journal of biochemistry 254 (1), 202-206
181998
M Husain, CM Gupta
Interactions of viral matrix protein and nucleoprotein with the host cell cytoskeletal actin in influenza viral infection
Current Science, 40-47
171997
A Arora, CM Gupta
Glycerol backbone conformation in phosphatidylcholines is primarily determined by the intramolecular stacking of the vicinally arranged acyl chains
Biochimica et Biophysica Acta (BBA)-Biomembranes 1324 (1), 47-60
161997
A Arora, CM Gupta
Novel thermal phase transition behavior of phosphatidylcholine analogs containing 1, 2, 4-butanetriol as their backbone
Biochimica et Biophysica Acta (BBA)-Biomembranes 1324 (1), 61-68
41997
A Surolia, AS Balasubramanian, AN Bhaduri, A Datta, CM Gupta, S Basu
Bimal Kumar Bachhawat-An obituary
Current Science (Bangalore) 71 (11), 932-933
11996
BL Dixit, CM Gupta
Defective amino acids transport in Saccharomyces cerevisiae cytoskeleton mutants.
MOLECULAR BIOLOGY OF THE CELL 7, 2251-2251
1996
K Balasubramanian, CM Gupta
Transbilayer phosphatidylethanolamine movements in the yeast plasma membrane: evidence for a protein‐mediated, energy‐dependent mechanism
European journal of biochemistry 240 (3), 798-806
251996
Antigen incorporation into liposomes results in the enhancement of IL-4 and IgG1 secretion: evidence for preferential expansion of Th-2 cells.JN Agrewala, M Owais, CM Gupta, GC
MishraCytokines and molecular therapy 2 (1), 59-65
421996
VK KALRA, CM GUPTA, A ZACHOWSKI
Chapter VI Lipid Asymmetry of Membranes
Manual on Membrane Lipids: With 46 Figures, 112
1996
VK Kalra, CM Gupta, A Zachowski, T Pomorski
Lipid asymmetry of membranes
Manual on Membrane Lipids, 112-143
21996
GC Varshney, CM Gupta
Liposomes mediated drug delivery in infectious diseases.
Proc Nalt Acad Sci (India) 66, 1-13
1996
M Owais, GC Varshney, A Choudhury, S Chandra, CM Gupta
Chloroquine encapsulated in malaria-infected erythrocyte-specific antibody-bearing liposomes effectively controls chloroquine-resistant Plasmodium berghei infections in mice
Antimicrobial agents and chemotherapy 39 (1), 180-184
2421995
A Agarwal, H Kandpal, HP Gupta, NB Singh, CM Gupta
Tuftsin-bearing liposomes as rifampin vehicles in treatment of tuberculosis in mice
Antimicrobial agents and chemotherapy 38 (3), 588-593
961994
CM GUPTA
Liposomes in Drug Delivery
Tropical Diseases: Molecular Biology and Control Strategies, 229
1994
.T Gudi, CM Gupta
hsp 70-like protein in rhesus erythrocyte cytosol and its interactions with membrane skeleton under heat and pathologic stress
Journal of Biological Chemistry 268 (28), 21344-21350
201993
M Owais, I Ahmed, B Krishnakumar, RK Jaina, BK Bachhawat, CM Gupta
Tuftsin‐bearing liposomes as drug vehicles in the treatment of experimental aspergillosis
FEBS letters 326 (1-3), 56-58
521993
J Kumar, CM Gupta
Membrane skeletal protein structure and interactions in human erythrocytes after their treatment
with diamide and calcium.
Indian Journal of Biochemistry & Biophysics 29 (2), 123-127
31992
I Ahmad, A Agarwal, A Pal, PY Guru, BK Bachhawat, CM Gupta
Tissue distribution and antileishmanial activity of liposomised Amphotericin-B in Balb/c mice §
Journal of biosciences 16 (4), 217-221
191991
S Chandra, AK Agrawal, CM Gupta
Chloroquine delivery to erythrocytes inPlasmodium berghei-infected mice using antibody-bearing liposomes as drug vehicles
Journal of biosciences 16 (3), 137-144
251991
S Misra, DP Singh, CM Gupta, RK Chatterjee, N Anand
Acanthocheilonema viteae in Mastomys natalensis: Effect of immunomodulators on establishment and course of infection
Medical science research 19 (2), 53-55
91991
N Anand, RK Chatterjee, CM Gupta
Immunomodulator and human health
Immunology: Perspectives in Reproduction and Infection. A Festschrift Volume …
11991
A Kumar, SRP Gudi, SM Gokhale, V Bhakuni, CM Gupta
Heat-induced alterations in monkey erythrocyte membrane phospholipid organization and skeletal protein structure and interactions
Biochimica et Biophysica Acta (BBA)-Biomembranes 1030 (2), 269-278
211990
CM Gupta
Membrane-associated cytoskeleton and transbilayer phospholipid asymmetry.
Indian Journal of Biochemistry & Biophysics 27 (6), 365-367
31990
CM Gupta
Is there any role of membrane bilayer‐skeleton interaction in maintaining the transmembrane phospholipid asymmetry in erythrocytes?
Biotechnology and Applied Biochemistry 12 (5), 506-511
111990
R Joshi, CM Gupta
Sulfate self-exchange and amino acid transport in calcium-loaded human erythrocytes
The Journal of membrane biology 117 (3), 233-242
31990
N Singh, RK Jain, CM Gupta, N Anand
Anti-stress activity in a muramyl-dipeptide.
Indian Journal of Experimental Biology 28 (7), 686-687
31990
SRP Gudi, A Kumar, V Bhakuni, SM Gokhale, CM Gupta
Membrane skeleton-bilayer interaction is not the major determinant of membrane phospholipid asymmetry in human erythrocytes
Biochimica et Biophysica Acta (BBA)-Biomembranes 1023 (1), 63-72
891990
U Sengupta, S Sinha, V Chaturvedi, RB Narayanan, CM Gupta
Coupling of proteins to liposomes and their role in understanding delayed type of hypersensitivity in human and mice
Journal of biosciences 15 (3), 235-238
21990
V Bhakuni, CM Gupta
Carbamyl phosphatidylcholine-cholesterol interactions in unilamellar vesicles
Biochimica et Biophysica Acta (BBA)-Biomembranes 982 (2), 216-222
41989
PY Guru, AK Agrawal, UK Singha, A Singhal, CM Gupta
Drug targeting in Leishmania donovani infections using tuftsin‐bearing liposomes as drug vehicles
FEBS letters 245 (1-2), 204-208
891989
RK Chatterjee, N Fatma, RK Jain, CM Gupta, N Anand
Litomosoides carinii in rodents: immunomodulation in potentiating action of diethylcarbamazine.
The Japanese Journal of Experimental Medicine 58 (6), 243-248
241988
P Joshi, CM Gupta
Abnormal membrane phospholipid organization in Plasmodium falciparum‐infected human erythrocytes
British journal of haematology 68 (2), 255-259
541988
CM Gupta
Red cell membrane alterations in malaria
Indian journal of biochemistry & biophysics 25 (1-2), 20-24
171988
U Sengupta, S Sinha, G Ramu, RK Lavania, CM Gupta
Soluble antigen of M. leprae coupled with liposomes elicits both” early” and” late” delayed hypersensitivity skin reactions
International journal of leprosy and other mycobacterial diseases 56 (1), 45-49
91988
N Khullar, CM Gupta, S Sehgal
Immune response studies in relation to protection induced by using MDP as an adjuvant in malaria
Immunological investigations 17 (1), 1-17
121988
CM Gupta
Stabilization mechanisms of transbilayer phospholipid asymmetry in erythrocyte membrane
Current Science, 1201-1209
91987
AK Agrawal, A Singhal, CM Gupta
Functional drug targeting to erythrocytes in vivo using antibody bearing liposomes as drug vehicles
Biochemical and biophysical research communications 148 (1), 357-361
651987
R Chandra, PC Joshi, VK Bajpai, CM Gupta
Membrane phospholipid organization in calcium-loaded human erythrocytes
Biochimica et Biophysica Acta (BBA)-Biomembranes 902 (2), 253-262
851987
P Joshi, GP Dutta, CM Gupta
An intracellular simian malarial parasite (Plasmodium knowlesi) induces stage-dependent alterations in membrane phospholipid organization of its host erythrocyte
Biochemical Journal 246 (1), 103-108
491987
A Kumar, S Daniel, SS Agarwal, CM Gupta
Abnormal erythrocyte membrane phospholipid organisation in chronic myeloid leukaemia
Journal of Biosciences 11 (1), 543-548
101987
RB Narayanan, G Ramu, S Sinha, U Sengupta, CM Gupta
Immunohistologic comparison between armadillo-derived leprosin and standard lepromin skin tests in leprosy patients
International Archives of Allergy and Immunology 82 (2), 202-207
41987
P Joshi, A Alam, R Chandra, SK Puri, CM Gupta
Possible basis for membrane changes in nonparasitized erythrocytes of malaria-infected animals
Biochimica et Biophysica Acta (BBA)-Biomembranes 862 (1), 220-222
191986
RK Jain, CM Gupta, RK Saxena, RP Saxena, KC Saxena, R Shukla, …
Synthesis, mass spectral characterization and immunoadjuvant activity of some novel lipophilic derivatives of muramyl dipeptides
Chemistry and physics of lipids 41 (3-4), 237-264
81986
K Agarwal, A Bali, CM Gupta
Effect of phospholipid structure on stability and survival times of liposomes in circulation
Biochimica et Biophysica Acta (BBA)-General Subjects 883 (3), 468-475
291986
CM Gupta, A Puri, RK Jain, A Bali, N Anand
Protection of mice against Plasmodium berghei infection by a tuftsin derivative
FEBS letters 205 (2), 351-354
381986
V Bhakuni, CM Gupta
Interactions of tuftsin with bovine serum albumin
FEBS letters 205 (2), 347-350
171986
A Singhal, CM Gupta
Antibody-mediated targeting of liposomes to red cells in vivo
FEBS letters 201 (2), 321-326
521986
CX George, RK Jain, CM Gupta, N Anand
Enhancement in anti‐Semliki Forest virus activity of ds RNA by a muramyl dipeptide
FEBS letters 200 (1), 37-41
131986
K Agarwal, A Bali, CM Gupta
Influence of the phospholipid structure on the stability of liposomes in serum
Biochimica et Biophysica Acta (BBA)-Biomembranes 856 (1), 36-40
451986
A Singhal, A Bali, CM Gupta
Antibody-mediated targeting of liposomes to erythrocytes in the whole blood
Biochimica et Biophysica Acta (BBA)-General Subjects 880 (1), 72-77
231986
W Curatolo, A Bali, CM Gupta
Phase behavior of carbamyloxyphosphatidylcholine, a sphingolipid analogue
Journal of pharmaceutical sciences 74 (12), 1255-1258
151985
A Kumar, CM Gupta
Transbilayer phosphatidylcholine distributions in small unilamellar sphingomyelin-phosphatidylcholine vesicles: effect of altered polar head group
Biochemistry 24 (19), 5157-5163
191985
CM Gupta, A Kumar, P Joshi
Role of membrane-associated cytoskeleton in maintenance of membrane structure
Journal of Biosciences 8 (1), 355-362
1985
N Khullar, CM Gupta, S Sehgal
Immunomodulation of experimental malaria by MDP.
Indian Journal of Malariology 22 (1), 21-27
41985
A Singhal, A Bali, RK Jain, CM Gupta
Specific interactions of liposomes with PMN leukocytes upon incorporating tuftsin in their bilayers
FEBS letters 178 (1), 109-113
411984
K Agarwal, A Bali, CM Gupta
Synthesis of carbamyl and ether analogs of phosphatidylcholines
Chemistry and physics of lipids 36 (2), 169-177
141984
A Kumar, CM Gupta
Transbilayer distributions of red cell membrane phospholipids in unilamellar vesicles
Biochimica et Biophysica Acta (BBA)-Biomembranes 769 (2), 419-428
331984
Y Takagaki, R Radhakrishnan, CM Gupta, HG Khorana
The membrane-embedded segment of cytochrome b5 as studied by cross-linking with photoactivatable phospholipids.
Journal of Biological Chemistry 258 (15), 9128-9135
801983
A Kumar, CM Gupta
Red cell membrane abnormalities in chronic myeloid leukaemia
Nature 303 (5918), 632-633
691983
A Kumar, CM Gupta
Effect of altered polar headgroup of phosphatidylethanolamines on transbilayer aminophospholipid distribution in sonicated vesicles
Biochimica et Biophysica Acta (BBA)-Biomembranes 730 (1), 1-9
191983
A Bali, S Dhawan, CM Gupta
Stability of liposomes in circulation is markedly enhanced by structural modification of their phospholipid component
FEBS letters 154 (2), 373-377
281983
W Curatolo, A Bali, CM Gupta
Metastable phase behavior of a sphingolipid analogue
Biochimica et Biophysica Acta (BBA)-Biomembranes 690 (1), 89-94
581982
W Curatolo, A Bali, CM Gupta
Metastable phase behavior of a sphingolipid analogue
Biochimica et Biophysica Acta (BBA)-Biomembranes 690 (1), 89-94
271982
KS Huang, MJ Liao, CM Gupta, N Royal, K Biemann, HG Khorana
The site of attachment of retinal in bacteriorhodopsin. The epsilon-amino group in Lys-41 is not required for proton translocation.
Journal of Biological Chemistry 257 (15), 8596-8599
441982
W CURATOLO, CM GUPTA, A BALI
METASTABLE PHASE-BEHAVIOR OF CEREBROSIDES AND A SPHINGOLIPID ANALOG
BIOPHYSICAL JOURNAL 37 (2), A99-A99
1982
CM Gupta, A Bali, S Dhawan
Modification of phospholipid structure results in greater stability of liposomes in serum
Biochimica et Biophysica Acta (BBA)-Biomembranes 648 (2), 192-198
311981
HS Banyal, GC Misra, CM Gupta, GP Dutta
Involvement of malarial proteases in the interaction between the parasite and host erythrocyte in Plasmodium knowlesi infections
The Journal of parasitology, 623-626
851981
CM Gupta, GC Mishra
Transbilayer phospholipid asymmetry in Plasmodium knowlesi-infected host cell membrane
Science 212 (4498), 1047-1049
761981
W Curatolo, R Radhakrishnan, CM Gupta, HG Khorana
Photoactivatable carbene-generating phospholipids: physical properties and use in detection of phase separations in lipid mixtures
Biochemistry 20 (5), 1374-1378
281981
CM Gupta, A Bali
Carbamyl analogs of phosphatidylcholines: synthesis, interaction with phospholipases and permeability behavior of their liposomes
Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 663 (2), 506-515
591981
GE Gerber, R Radhakrishhnan, CM Gupta, HG Khorana
Interaction of cholesterol with photoactivable phospholipids in sonicated vesicles
Biochimica et Biophysica Acta (BBA)-Biomembranes 640 (3), 646-654
101981
S Kumar, RC Gupta, CM Gupta, N Anand
A new synthetic approach to 8-aza analogs of prostaglandins
Indian Journal of Chemistry 20, 595-596
1981
RK Jain, CM Gupta, N Anand
Synthesis of peptidylglycophospholipids, novel derivatives of muramyl-dipeptide
Tetrahedron Letters 22 (24), 2317-2320
311981
Y Takagaki, CM Gupta, HG Khorana
Thiols and the diazo group in photoaffinity labels
Biochemical and Biophysical Research Communications 95 (2), 589-595
211980
R Radhakrishnan, CM Gupta, B Erni, RJ Robson, W Curatolo, …
Phospholipids containing photoactivable groups in studies of biological membranes.
Annals of the New York Academy of Sciences 346, 165-198
261980
CM Gupta, CE Costello, HG Khorana
Sites of intermolecular crosslinking of fatty acyl chains in phospholipids carrying a photoactivable carbene precursor
Proceedings of the National Academy of Sciences 76 (7), 3139-3143
801979
CM Gupta, R Radhakrishnan, GE Gerber, WL Olsen, SC Quay, …
Intermolecular crosslinking of fatty acyl chains in phospholipids: use of photoactivable carbene precursors
Proceedings of the National Academy of Sciences 76 (6), 2595-2599
901979
W Curatolo, CM Gupta, HG KHORANA
MODEL MEMBRANE STUDIES USING PHOTO-CHEMICAL CROSSLINKING REAGENTS
BIOPHYSICAL JOURNAL 25 (2), A181-A181
11979
CM GUPTA, AP HOPE, GH JONES, JG MOFFATT
SYNTHESIS OF 2-DEAZAOXOFORMYCIN
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 175 (MAR), 40-40
1978
JG MOFFATT, HP ALBRECHT, GH JONES, DB REPKE, G TRUMMLITZ, …
ADVANCES IN THE SYNTHESIS OF C-GLYCOSYL NUCLEOSIDES
Chemistry and Biology of Nucleosides and Nucleotides, 359-380
1978
CM Gupta, R Radhakrishnan, HG Khorana
Glycerophospholipid synthesis: improved general method and new analogs containing photoactivable groups
Proceedings of the National Academy of Sciences 74 (10), 4315-4319
5551977
CM GUPTA, R RADHAKRISHNAN, GE GERBER, Y TAKAGAKI, …
STUDY OF LIPID-LIPID AND LIPID-PROTEIN INTERACTIONS IN BIOLOGICAL-MEMBRANES USING PHOSPHOLIPIDS CONTAINING PHOTOREACTIVE GROUPS
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 174 (SEP), 179-179
1977
CM Gupta, GH Jones, JG Moffatt
C-glycosyl nucleosides. 9. An approach to the synthesis of purine-related C-glycosides
The Journal of Organic Chemistry 41 (18), 3000-3009
381976
GB Singh, CM Gupta, S Nityanand, RC Srimal, N Nand, BN Dhawan
1, 3-Bistertiary-aminomethyl pyrrocolines, a new class of hypotensive agents.
Indian J Exp Biol
11976
JG MOFFATT, GH JONES, HP ALBRECHT, D REPKE, H OHRUI, …
PROGRESS IN SYNTHESIS OF C-GLYCOSYL NUCLEOSIDES
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 172 (SEP 3), 62-62
1976
CM GUPTA, N ANAND
NMR SPECTRA OF 1, 2, 4-SUBSTITUTED 3-PHENYL-CYCL (3.2. 2) AZINES.
1974
CMAL GUPTA
SYNTHESIS OF BIOLOGICALLY ACTIVE QUINAZOLONES AND RELATED COMPOUNDS
Agra University Journal of Research: Science 20 (Pt II), 139-142
1972
MM Dhar, C Singh, AW Khan, AJ Arif, CM Gupta, AP Bhaduri
Studies on the cell-free synthesis of echinomycin and an echinomycin analogue
Pure and Applied Chemistry 28 (4), 469-474
51971
SRIVASTA. PC, CM GUPTA, AP BHADURI
ONE STEP SYNTHESIS OF 4-OXO-DELTA2-PYRROLINES FROM IMINOESTERS
TETRAHEDRON LETTERS, 1975-&
1971
CM Gupta, AP Bhaduri, NM Khanna
Biologically active quinazolones and related compounds
JOURNAL OF SCIENTIFIC & INDUSTRIAL RESEARCH 30 (3), 101-&
71971
CM Gupta, AP Bhaduri, NM Khanna, SK Mukherjee
NOVEL CLASS OF HYPOGLYCAEMIC AGENTS-SYNTHESES AND SAR IN 2-SUBSTITUTED 4 (3H)-QUINAZOLONES, 2-SUBSTITUTED 4-HYDROXYPOLYMETHYLENE [5, 6] PYRIMIDINES AND 3-SUBSTITUTED 4-OXO …
Indian Journal of Chemistry 9 (3), 201-+
371971
AJ Arif, C Singh, AP Bhaduri, CM Gupta, AW Khan, MM Dhar
Actinomycetes studies. II. Cell-free synthesis of echinomycin and an echinomycin analogue
Indian journal of biochemistry 7 (3), 193-195
111970
CM Gupta, AP Bhaduri, NM Khanna
REACTION OF 2-BENZYLTHIO-3-PHENYLQUINAZOLO-4-THIONE WITH HYDRAZINE
INDIAN JOURNAL OF CHEMISTRY 8 (12), 1055-&
31970
CM Gupta, AP Bhaduri, NM Khanna
Reaction of hydrazine with substituted aminomethylenemalonates: Rearrangement of Michael adduct to give triazoles and pyrazole
Tetrahedron 26 (12), 3069-3071
21970
AW Khan, AP Bhaduri, CM Gupta, MM Dhar
Actinomycetes studies. 1. Microbiological synthesis of quinazomycin, an echinomycin analogue containing one quinazol-4-one-3-acetyl residue
Indian journal of biochemistry 6 (4), 220-221
91969
CM Gupta, ST Husain, AP Bhaduri, NM Khanna, SK Mukherjee
New potent blood sugar lowering compound
Nature 223 (5205), 524-524
341969
CM Gupta, AP Bhaduri, NM Khanna
RING OPENING OF 3-AND 2, 3-DISUBSTITUTED-4-QUINAZOLONES UNDER FRIEDEL-CRAFTS CONDITION
INDIAN JOURNAL OF CHEMISTRY 7 (5), 527-&
11969
CM Gupta, AP Bhaduri, NM Khanna
DRUGS ACTING ON CNS-SYNTHESES AND STRUCTURE-ACTIVITY RELATIONSHIP IN 2-METHYL-3-(0-TOLYL)-QUINAZOLINE-4-ONE ANALOGS
Indian Journal of Chemistry 7 (9), 866-&
61969
CM Gupta, AP Bhaduri, NM Khanna
BIOLOGICALLY ACTIVE IMIDAZOLO [5, 6-B], PYRAZINO [5, 6] AND DIAZEPINO [5, 6] QUINAZOLINONES
INDIAN JOURNAL OF CHEMISTRY 7 (11), 1166-&
31969
CM Gupta, AP Bhaduri, NM Khanna
Drugs acting on the central nervous system. Syntheses of substituted quinazolinones and quinazolines and triazepino-and triazocinoquinazolinones
Journal of Medicinal Chemistry 11 (2), 392-395
1321968
CM Gupta, AP Bhaduri, KM Khanna
Drugs acting on CNS: Syntheses of 2-substituted & 2, 3-disubstituted benzo (6, 7) quinazoline-4-ones
Indian journal of chemistry 6, 621-623
21968
CM Gupta, AP Bhaduri, NM Khanna
CYCLIZATION REACTIONS OF METHYL 2-CHLORO-3, 5-DINITROBENZOATE
INDIAN JOURNAL OF CHEMISTRY 6 (12), 758-&
51968

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